Beginning with your own blood, treatment planning can be tailored more closely to your individual condition.
PRE (Platelet-Rich Exosome) is sourced from platelets in the patient’s own blood. After collection, the sample is sent through a specialized preparation, testing, storage, and delivery process. A physician then reviews your medical history, skin or scalp condition, goals, and product documents before planning how PRE may be used.
PRE is not a ready-made ingredient package, and a concentration or particle count alone cannot predict an outcome. At Geo Aesthetic Clinic, we focus on whether the source is clear, the report is interpreted correctly, and PRE has an appropriate role in your overall care plan.
Consultations are available at all locations: Taipei, Hsinchu, Chiayi, Kaohsiung, and Kinmen. Blood collection and treatment dates depend on the physician’s assessment, clinic schedule, and preparation timeline. View clinic locations, hours, and booking information.
What is PRE?
PRE is an autologous platelet-derived exosome material prepared from platelets in the patient’s own blood. Following a professional preparation and testing process, a physician evaluates how it may be used according to the patient’s medical history, health considerations, and treatment goals.
PRE is not completed immediately after blood collection at the clinic. Preparation, testing, storage, and delivery are required. The actual timeline, number of prepared units, and clinical arrangement must follow the medical assessment and formal preparation documents for that case.
PRE is more than a vial
It is easy to focus on particle counts or growth-factor names. In medical planning, however, these are only part of the information that needs to be considered.
Autologous source
PRE begins with the patient’s own blood. An autologous source does not mean it is appropriate for everyone, so blood-collection conditions, medical history, and medication still need review.
Specialized preparation
The collected sample is sent through a specialized preparation process rather than being completed immediately in the consultation room.
Document interpretation
Test information helps explain the prepared material, but a single value cannot be converted directly into a visible result.
Individual planning
Treatment area, method, number of sessions, intervals, and combinations with other care are planned by a physician.
How are PRE and PRP different?
Both may begin with the patient’s own blood, but their final form, preparation location, waiting time, storage requirements, and clinical arrangements differ. The relevant question is not which one is “more advanced,” but which process better fits the treatment goal, health considerations, and acceptable schedule.
| Comparison | PRE | PRP |
|---|---|---|
| Source | Platelets from the patient’s own blood | The patient’s own blood |
| Final form | Professionally prepared platelet-derived exosome material | Platelet-rich plasma prepared by centrifugation |
| Preparation | Specialized preparation, testing, and storage management | Blood collection and centrifugation are generally completed at a medical clinic |
| Timing | Preparation and testing time is required | Arranged according to the clinic’s blood-collection process |
| Planning | Medical history, goals, product documents, and physician assessment | Current blood sample, goals, and physician assessment |
PRE and PRP should not be ranked as a simple higher- or lower-tier choice, and suitability cannot be determined by concentration, particle count, or a single test result alone.
How should growth-factor information be read?
BIONET materials mention PDGF, IGF-1, and Angiogenin. These names may help patients understand the product documents, but they cannot by themselves predict an individual clinical response.
PDGF | Platelet-derived growth factor
PDGF is one of the growth factors studied in cell signaling and tissue repair. If it appears in the product documents, a physician interprets it together with the treatment goal and individual condition rather than treating the value as a guarantee.
IGF-1 | Insulin-like growth factor 1
IGF-1 is associated with cellular growth, metabolism, and tissue responses. A report value alone cannot indicate how much the skin or scalp will change; diagnosis, treatment method, and follow-up remain essential.
Angiogenin
Angiogenin is a protein studied in relation to angiogenesis and cellular signaling. Its meaning in a prepared product should be explained from the formal report and should not be converted into a promise of individual results.
A test report provides additional information for the medical team. It is not a scorecard or a guarantee of outcome.
From blood-collection booking to physician assessment
- Consultation and booking: Treatment goals, medical history, medications, blood-related considerations, and recent procedures are reviewed first.
- Blood collection and aseptic preparation: The sample is sent through the formal preparation process. Collection volume, number of prepared units, and timing follow the selected plan and documents.
- Testing and documentation: Relevant preparation or testing information is provided according to the plan and explained by a qualified professional.
- Refrigerated storage and cold-chain delivery: Storage conditions, expiry, and use timing follow the product label and formal documents.
- Physician reassessment and planning: Health status, treatment area, product information, and recent procedures are reviewed again before use and follow-up are arranged.
Skin and scalp concerns require different questions
Skin recovery and condition management
For concerns such as fine lines, dryness, unstable skin condition, or recovery planning, the physician first assesses the cause, current infection or acute inflammation, recent laser or microneedling procedures, and the role PRE may have in the overall plan.
PRE does not replace the diagnosis of a skin disease, and not every skin concern is treated in the same way. Suitability, combinations, and the observation period are adjusted according to the skin condition and actual response.
Scalp and hair-loss assessment
For concerns about hair density, roots, or scalp condition, the first step is to assess the pattern and possible cause of hair loss. Genetics, hormones, stress, nutrition, disease, and medication may all contribute.
After the cause is considered, a physician can discuss whether PRE has an appropriate role, whether medication or other treatment is needed, and how progress should be followed. A laboratory value or a single case image cannot predict the same result for everyone.
What should you tell your physician?
Please disclose low platelet counts, platelet dysfunction or other blood disorders, acute or chronic infection, fever, significant medical history, medication that may affect clotting or platelet function, pregnancy, plans for pregnancy, breastfeeding, and recent dental work, surgery, injections, laser treatments, or other procedures.
Do not stop medication for blood collection or treatment without medical advice. Suitability, timing, and method of use require an individual assessment.
Frequently asked questions
Can PRE directly replace PRP?
Not necessarily. Their final form, preparation process, storage requirements, timing, and clinical arrangements differ. The physician considers the treatment goal, medical history, and preferred schedule.
Does an autologous source mean there is no risk?
No. An autologous source does not make PRE appropriate for everyone and does not replace infection control, blood-collection screening, or review of medical history and medications.
Why can’t particle count alone predict the result?
Particle count is only one part of the product information. Individual condition, goals, method, treatment area, diagnosis, and aftercare also affect the clinical response.
Are higher PDGF, IGF-1, or Angiogenin values always better?
No. The testing method, reference range, product condition, and individual medical context must be considered together. A single high or low value is not an outcome guarantee.
How many sessions can follow one blood collection?
Collection volume, number of prepared units, and scheduling vary by plan, individual condition, and formal preparation documents. The physician explains the arrangement after the preparation result is confirmed.
Can PRE be combined with laser or microneedling procedures?
This can be discussed with a physician. Whether treatments are combined, their order, and the interval depend on the goal, area, skin condition, risks, recent procedures, and expected recovery.
Why is PRE not used immediately after blood collection?
PRE requires specialized preparation, testing, storage, and delivery. The timeline is confirmed for each case with the preparation facility.
Can I take the prepared product home for storage?
Storage, delivery, and use should follow the formal documents and clinic process. Patients should not change the storage conditions independently.
Bring your questions to the consultation
Understanding yourself is where thoughtful care begins.
Bring the concerns that matter most to you, your previous procedures, medications, and scheduling needs. Geo Aesthetic Clinic begins by asking whether PRE is appropriate and explains the reasoning behind each step rather than placing every patient into a fixed package.
View clinic locations and booking information
Medical review: Dr. Hsieh Hsun-Cheng | Reviewed: September 27, 2026 | Updated: September 28, 2026
This page provides general educational information and an overview of the assessment process. It does not replace a medical diagnosis. Specific indications, method, number and interval of sessions, risks, contraindications, and expected responses require a physician’s assessment and must follow the relevant medical documents.
